What is Retinol and what are its benefits for skin?

- fine lines
- wrinkle
- enlarged pores
- uneven skin texture
- hyperpigmentation
Caution:
- Retinol makes the skin more sensitive to UV damage, so it is best used at night. If you must use it during the day, you must use sunscreen to protect your skin from the sun.
- Pregnant women are generally advised to avoid taking retinol. If you think you are pregnant or plan to become pregnant sometime in the near future, talk to your doctor about retinol.

Fig.1. ROL improves the visible appearance of fine lines. Representative images of a volunteer treated with 0.1% ROL at baseline, 24 and 36 weeks. Arrows point to fine lines that improve their appearance in the course of the study.
Fig.2. ROL improves the three-dimen-sional appearance of fine lines. Representative surface profilometry images demonstrating the three-dimensional appearance of fine lines of a volunteer treatedwith 0.1% ROL in the course of the study. The imaged area corresponds to the crow'sfeet region on the side of the eyes.
(Skin Pharmacol Physiol 2009;22:200–209. G. Bellemère, G. Stamatas, V. Bruère, C. Bertin, N. Issachar, T. Oddos)

Fig.6. ROL-induced increase in epidermal thickness ex vivo in human skin explants. ROL at a concentration of 0.1% was appliedonto skin explants for 48 h. Skin histology was visualized on day 0 (DO) and day 2 (48 h of incubation, D2) after Masson trichrome staining of the explants.
(Skin Pharmacol Physiol 2009;22:200–209. G. Bellemère, G. Stamatas, V. Bruère, C. Bertin, N. Issachar, T. Oddos)

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