Retinol is the gold standard in anti-aging skincare. Of course, it's backed by decades of medical research and dermatologists proving it works well for skin ageing.

Retinol (a vitamin A compound) has recently seen a mainstream revival, as beauty brands around the world have started using the collagen-stimulating ingredient. Great for helping keep skin elastic and smooth, retinol works deep in the lower layers of the skin to help produce healthy cells. Retinol occurs naturally in the skin and is proven to help improve fine lines, wrinkles and skin texture. It also helps reduce oxidative damage.

Retinol is mainly used to improve the following skin conditions:

• fine lines
• wrinkle
• enlarged pores
• uneven skin texture
• hyperpigmentation

Caution:

• Retinol makes the skin more sensitive to UV damage, so it is best used at night. If you must use it during the day, you must use sunscreen to protect your skin from the sun.
• Pregnant women are generally advised to avoid taking retinol. If you think you are pregnant or plan to become pregnant sometime in the near future, talk to your doctor about retinol.

Fig.1. ROL improves the visible appearance of fine lines. Representative images of a volunteer treated with 0.1% ROL at baseline, 24 and 36 weeks. Arrows point to fine lines that improve their appearance in the course of the study.

Fig.2. ROL improves the three-dimen-sional appearance of fine lines. Representative surface profilometry images demonstrating the three-dimensional appearance of fine lines of a volunteer treatedwith 0.1% ROL in the course of the study. The imaged area corresponds to the crow'sfeet region on the side of the eyes. 

(Skin Pharmacol Physiol 2009;22:200–209. G. Bellemère, G. Stamatas, V. Bruère, C. Bertin, N. Issachar, T. Oddos)

Fig.6. ROL-induced increase in epidermal thickness ex vivo in human skin explants. ROL at a concentration of 0.1% was appliedonto skin explants for 48 h. Skin histology was visualized on day 0 (DO) and day 2 (48 h of incubation, D2) after Masson trichrome staining of the explants. 

(Skin Pharmacol Physiol 2009;22:200–209. G. Bellemère, G. Stamatas, V. Bruère, C. Bertin, N. Issachar, T. Oddos)

HD retinol serum protects your skin from the signs of ageing. It helps to soothe away the look of wrinkles and can unclog pores to clear up acne. Enriched with Vitamin E and Hyaluronic Acid, the serum improves texture and tone for a smoother, firmer, more radiant complexion.

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